DESCRIPTION:

Prednisone is a biologically inert glucocorticoid which is converted to prednisolone in the liver. It has the same chemical relationship to prednisolone as cortisone has to hydrocostisone.

FORMULATION:

Each film coated tablet contains:
Prednisone …………..1 mg
Each Tablet contains:
Prednisone …………..5 mg
Each Tablet contains:
Prednisone …………..10 mg
Each film coated tablet contains:
Prednisone …………..20 mg
Each film coated tablet contains:
Prednisone …………..30 mg
Each film coated tablet contains:
Prednisone …………..50 mg
Each 5 mL (1 teaspoonful) contains:
Prednisone …………..10 mg

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INDICATION:

Endocrine, rheumatic and hematologic, disorders, allergic and edematous states, collagen, dermatologic and opthalmic repiratory and neoplastic disease.

DOSAGE:

Generally 5-25 mg daily to a maximum of 60 mg daily in divided doses or as prescribed by the physician.

CONTRAINDICATION:

Gastric and duodenal ulcers, systemic fungal infections, certain viral infections and hypersensitivity to glucocorticoids, glaucoma, live vaccines, psychoses or severe
psychoneuroses.

PRECAUTIONS:

Heart failure, recent myocardial infarction, or hypertension, diabetes mellitus, epilepsy, glaucoma, hypothyroidism, hepatic failure, osteoporosis, peptic ulceration, psychoses or severe effective disorders, and renal impairment.

PHARMACOKINETICS:

In general, corticosteroids are readily absorbed from gastrointestinal tract. They are also well absorbed from sites of local application, and are rapidly distributed to all body tissues. They cross
the placenta and may be excreted in small amount in breast milk. Metabolism is mainly in the liver but also in the kidney. while excretion is in the urine.

ADVERSE EFFECTS:

Fluid and electrolyte disturbances, psychiatric disturbances, Cushingoid state, hirsutism, visual disturbances, growth retardation, skin atrophy, facial erythema, aseptic osteonecrosis and amenorrhea.

CAUTION:

Foods, Drugs, Devices and Cosmetics Act prohibits dispensing without prescription.

AVAILABILITY:

Prednisone 1 mg film coated tablet
Blister Pack x 20’s – Box of 100’s

Prednisone 5 mg tablet
Blister Pack x 10’s – Box of 100’s

Prednisone 10 mg tablet
Blister Pack x 10’s – Box of 100’s and 500’s

Prednisone 20 mg film coated tablet
Blister Pack x 10’s – Box of 30’s and 100’s

Prednisone 30 mg film coated tabet
Blister Pack x 10’s – Box of 30’s and 100’s

Prednisone 50 mg film coated tabet
Blister Pack x 10’s – Box of 30’s

Prednisone 10 mg/ 5 mL suspension
30 mL and 60 mL Amber bottle

STORAGE CONDITION:

Store at temperature not exceeding 30 degree Celcius.